Gallstones

At Digestive & Liver Surgery, Dr Victor Lee Tswen Wen and Dr Tan Ek Khoon, both Senior Consultant Surgeons at the practice, assess and treat gallstones at Gleneagles Hospital, Mount Elizabeth Orchard Hospital, Mount Alvernia Hospital and HMI Medical Centre.

Gallstones are small, hardened deposits that form in the gallbladder, a small organ located beneath the liver that stores bile, the digestive fluid used to break down fats.

Gallstones develop when certain substances in bile, such as cholesterol or bilirubin, become too concentrated and begin to crystallise. Over time, these crystals can grow into stones that vary in size, number, and composition.

Understanding what gallstones are and how they form can help you make sense of the condition and the treatment options available in Singapore.

gallstones illustration

Types of Gallbladder Stones

Cholesterol Stones

These are the most common types of gallstones. Cholesterol stones form when bile contains more cholesterol than can be dissolved, causing an excess amount to crystallise and gradually form solid stones within the gallbladder.

Pigment Stones

Pigment stones are made primarily of bilirubin, a substance produced when the body breaks down old red blood cells. These stones tend to be darker in colour and may develop in people with certain liver conditions, infections of the bile ducts, or blood disorders that increase bilirubin levels.

a medical officer showing 3D model of the digestive system

Causes of Gallstones

Gallstones can develop when the normal movement and storage of bile in the gallbladder is disrupted.

Bile is produced by the liver and stored in the gallbladder before being released into the small intestine to help digest fats. When this system does not function as it should, bile can remain in the gallbladder for longer than usual, allowing solid particles to gradually develop.

Several factors may contribute to this process:

  • When the gallbladder does not empty fully during digestion, bile can remain inside for longer periods and become more concentrated.
  • Hormones such as oestrogen can change how bile is produced and stored, which may increase the chance of gallstones forming.
  • Your body weight and metabolism can affect how the body processes fats and bile.
  • Losing weight quickly can change how the liver releases bile, which may increase the risk of gallstones forming.
  • Some liver diseases, blood disorders, or digestive conditions can influence bile composition or flow.
  • Diets that are very high in fat or refined carbohydrates, or very low in fibre, may contribute to changes in bile balance over time.
Are you worried about gallstones?

Get a clear diagnosis and treatment plan from our surgeons at Digestive & Liver Surgery.

Common Symptoms of Gallstones

Here’s what you may experience if you have gallstones:

  • Sudden pain in the right upper abdomen
  • Pain in the centre of the abdomen below the breastbone (epigastric pain)
  • Pain that spreads from the abdomen to the back
  • Pain that radiates to the right shoulder
  • Abdominal bloating, which may feel worse after meals or at night
  • Nausea and vomiting

More severe symptoms may indicate complications from the stones found in your gallbladder and require treatment. These may include:

  • Severe abdominal pain
  • Fever
  • Jaundice (yellowing of the skin or eyes)

It’s also possible to have gallstones without experiencing any symptoms. In many cases, gallstones are discovered incidentally during imaging tests performed for other medical reasons.

gallbladder illustration

Who Is at Risk of Developing Gallstones?

You may have a higher likelihood of developing gallstones if you:

  • Are female, as hormonal changes can affect bile composition
  • Are over 40 years old
  • Have a family history of gallstones
  • Are overweight or obese
  • Have experienced rapid weight loss
  • Are pregnant
  • Have certain medical conditions, such as liver disease, diabetes, or blood disorders
  • Follow a diet high in fat or refined carbohydrates and low in fibre
a lady having stomach pain

Who Should You See First for Gallstones?

If an ultrasound has found gallstones, or you have had repeated upper abdominal pain after meals, the next step depends on how you’re feeling.

Booking a Specialist Directly

In the private sector in Singapore, you can book a specialist appointment directly. A GP referral is not required, although a referral letter is useful, as it carries your history and any tests already done. If you are seeking subsidised treatment at a public hospital, a referral from a polyclinic or GP is needed.

Gallstones are managed by a general surgeon or, where the bile duct and liver may be involved, a hepatopancreatobiliary surgeon. At Digestive & Liver Surgery, gallstones are seen by Dr Victor Lee Tswen Wen and Dr Tan Ek Khoon.
Who Should You See First for Gallstones

When to Go to A&E Instead of Booking an Appointment

Some gallstone presentations are emergencies and should not wait for a clinic appointment. Go to A&E if you have:

  • Severe abdominal pain that does not settle after several hours
  • Fever or chills alongside abdominal pain
  • Yellowing of the skin or eyes (jaundice)
  • Persistent vomiting

These can indicate cholecystitis, bile duct obstruction, cholangitis or pancreatitis, all of which are described in the complications section below.

What to Bring to Your First Appointment

  • Any ultrasound, CT or MRI report, and the images if you have them
  • Recent blood test results, particularly liver function tests
  • A list of your current medications, including blood thinners
  • Your referral letter, if you have one
  • Your insurance details

Gallbladder Stones Diagnosis

At Digestive & Liver Surgery, we typically begin with a clinical assessment and imaging tests to confirm the presence of stones and evaluate your gallbladder and bile ducts.

Depending on your symptoms and medical history, you may be asked to undergo one or more of the following investigations:

  • Ultrasound is usually the first test performed. It allows us to visualise gallstones, assess their size and number, and examine the gallbladder.
  • CT or MRI scans to evaluate abdominal pain further or to identify complications related to gallstone disease.
  • Blood tests, which help us check for signs of infection, inflammation, bile duct obstruction, pancreatitis, or jaundice.
  • Endoscopic ultrasound (EUS): During this procedure, a thin endoscope is passed through the mouth into the stomach and the first part of the small intestine (duodenum). This allows us to obtain detailed images and detect stones that may be located in the bile ducts.
  • Endoscopic retrograde cholangiopancreatography (ERCP): If stones are found in the bile duct, this may be performed to locate and remove them during the same procedure.

Do You Need Surgery for Gallstones?

If an ultrasound has found gallstones, or you have had repeated upper abdominal pain after meals, the next step depends on how you’re feeling.

When Surgery Is Usually Recommended

  • Recurrent biliary colic, meaning repeated episodes of upper abdominal pain caused by the stones
  • Cholecystitis, inflammation of the gallbladder
  • Bile duct obstruction, where a stone has moved into the bile duct
  • Gallstone pancreatitis
  • Haemolytic anaemia
  • An increased risk of gallbladder cancer

When Monitoring Is Usually Appropriate

If gallstones were found incidentally on a scan and have never caused symptoms, treatment is usually not required, and monitoring is recommended instead. Most people with gallstones never develop symptoms.
Do You Need Surgery for Gallstones
a medical officer explaining gallstones treatment to a patient

Gallstones Treatment

Your treatment will depend largely on whether your gallstones are causing symptoms.

Non-Surgical Treatment for Gallstones

Non-surgical options for gallstones are limited, and they are not suitable for most patients.

Bile acid dissolution therapy uses ursodeoxycholic acid to dissolve stones gradually. It only works on small cholesterol stones, treatment takes months, and stones frequently return once the medication is stopped, because the gallbladder that formed them is still in place.

Extracorporeal shock wave lithotripsy, which breaks stones up using sound waves, is used for kidney stones but is rarely used for gallstones in Singapore. The fragments still have to leave through the bile duct, which can cause further problems.

Procedures that remove the stones but keep the gallbladder are not standard practice. A gallbladder that has formed stones tends to form them again, so removing the stones alone does not treat the underlying problem.

For this reason, gallbladder removal remains the definitive treatment for gallstones that are causing symptoms. Dr Victor Lee Tswen Wen and Dr Tan Ek Khoon will explain which options apply in your case.

If gallstones are detected during an ultrasound but you don’t experience symptoms, treatment is usually not required. Monitoring your condition may be sufficient.

If gallstones begin to cause pain or complications, gallbladder removal surgery may be recommended as part of your treatment plan. Surgery may also be considered if you have certain medical conditions, such as haemolytic anaemia, or if there’s an increased risk of gallbladder cancer.

In most cases, we perform cholecystectomy using laparoscopic (keyhole) surgery. During the procedure, we remove the gallbladder through several small incisions in your abdomen using specialised instruments.

You may be able to return home on the same day or after an overnight stay in the hospital, depending on your recovery.

In more complex cases, an open surgical procedure may be required. This involves a larger incision in the abdomen and usually requires a longer hospital stay.

How Soon Do You Need Gallbladder Surgery After Diagnosis?

How quickly you need surgery depends on how the gallstones are behaving, not on when they were found.

No Symptoms

If the stones were found incidentally and have never caused symptoms, there is no timeframe. We monitor and operate only if symptoms develop.

Symptoms but Stable

If you have had one or more episodes of biliary pain but are well now, surgery is usually planned as an elective procedure. At Digestive & Liver Surgery, this typically involves an appointment for clinic review as quickly as the same day or within 24 hours. Subsequent elective surgery can be planned within 1 to 2 weeks, or at the patient’s own schedule and convenience. Waiting longer may carry a risk of further attacks, which may then need emergency surgery.

Emergency Presentation

If you present with acute cholecystitis, bile duct obstruction, cholangitis or gallstone pancreatitis, surgery is usually performed during the same hospital admission rather than being scheduled for later. These complications are described in the section below.

What Are the Complications of Gallstones?

Gallstones with complications are usually treated as emergency cases. These include:

  • Cholecystitis (gallbladder inflammation): When a gallstone blocks the opening of the gallbladder, leading to inflammation and persistent abdominal pain.
  • Bile duct obstruction (choledocholithiasis): A gallstone may move from the gallbladder into the bile duct and block the flow of bile.
  • Pancreatitis: If a gallstone blocks the pancreatic duct, it can trigger inflammation of the pancreas.
  • Cholangitis: Infection can develop in the bile ducts if bile flow is blocked for a prolonged period.
a man holding his stomach in pain

How to Prevent Gallstones

Gallstones cannot always be prevented, but certain lifestyle habits may help reduce your risk.

Maintaining a healthy body weight and eating a balanced diet can support normal bile function.

Rapid weight loss and crash dieting can increase the risk of gallstones, so gradual and sustainable weight management is generally recommended.

Ongoing Gallbladder Pain or Gallstones?

Gallstones can lead to recurring pain or complications if they continue to block the flow of bile. Speak with our surgeons at Digestive & Liver Surgery to determine what kind of gallstones treatment you need.

Frequently Asked Questions

Can gallstones go away naturally?

No, gallstones usually don’t go away on their own. Once formed, they tend to remain in the gallbladder unless they are removed or pass into the bile ducts.

Untreated gallstones may lead to gallbladder infection, bile duct obstruction, or pancreatitis.

Yes, it can be safe to live with gallstones if they do not cause symptoms. In such cases, we may recommend monitoring rather than surgery unless pain or complications develop.

Non-surgical options are limited. Bile acid dissolution therapy can dissolve small cholesterol stones, but it takes months and stones often return. At Digestive & Liver Surgery, gallbladder removal remains the definitive treatment for gallstones causing symptoms. See Non-Surgical Treatment for Gallstones above for the full explanation.

Surgery is usually recommended when gallstones cause symptoms or complications rather than based on their size alone. Recurrent pain, inflammation, or bile duct blockage are common reasons surgery may be recommended.

No. Gallstones found incidentally that have never caused symptoms are usually monitored rather than removed. At Digestive & Liver Surgery, we recommend surgery when stones cause recurrent pain, inflammation, bile duct obstruction or pancreatitis, or when specific risk factors for gallbladder cancer are present.

It depends on your symptoms. Gallstones without symptoms have no timeframe. If you have had biliary pain, Digestive & Liver Surgery will plan elective surgery, since waiting risks a further attack. Acute cholecystitis, cholangitis or gallstone pancreatitis is usually operated on during the same hospital admission.

No referral is required to book a private specialist appointment, though a referral letter is useful because it carries your history and previous tests. A polyclinic or GP referral is needed for subsidised treatment at a public hospital. Digestive & Liver Surgery accepts direct bookings at all four locations.

Gallstones are treated by general surgeons and by hepatopancreatobiliary surgeons, who specialise in the liver, gallbladder, bile duct and pancreas. Digestive & Liver Surgery is a hepatopancreatobiliary practice and treats gallstones at Gleneagles Hospital, Mount Elizabeth Orchard Hospital, Mount Alvernia Hospital and HMI Medical Centre.

Complicated cases involve the bile duct, such as stones that have moved out of the gallbladder, or severe inflammation. These need a surgeon who operates on the bile duct and liver. Digestive & Liver Surgery manages combined ERCP and surgery for bile duct stones within the same team.

Ask how many gallbladder operations the surgeon performs each year, whether they manage bile duct problems themselves or refer them on, and which hospitals they operate at. Digestive & Liver Surgery performs approximately 120 to 150 gallbladder surgeries a year across four private hospitals.

Both perform gallbladder removal. The difference matters when the bile duct is involved, which is where the serious risk in this operation lies. Dr Victor Lee Tswen Wen and Dr Tan Ek Khoon are hepatopancreatobiliary surgeons, so bile duct problems are managed within the same team.

Digestive & Liver Surgery performs approximately 120 to 150 gallbladder surgeries each year. These are carried out by Dr Victor Lee Tswen Wen and Dr Tan Ek Khoon, both Senior Consultant Surgeons, using laparoscopic keyhole techniques in the majority of cases.

Dr Victor Lee Tswen Wen and Dr Tan Ek Khoon operate at Gleneagles Hospital, Mount Elizabeth Orchard Hospital, Mount Alvernia Hospital and HMI Medical Centre. Digestive & Liver Surgery holds clinics at all four, so gallstone patients can choose the location that suits them best.

About Us

Senior Consultant Surgeon

Senior Consultant Surgeon

Mount Elizabeth Orchard

6737 8878

Gleneagles Hospital

6475 1488

Contact Us

Enquiry Form

Fill out our Enquiry Form and our team will be in touch with you shortly.

Video Consult

Schedule a Video Consult to speak with our specialists from the comfort of your home.

Mount Elizabeth Orchard

6737 8878

Gleneagles Hospital

6475 1488

Specialised Expertise
for your Liver Health

Professional Care You Can trust

Mount Elizabeth Orchard

6737 8878

Gleneagles Hospital

6475 1488

New DLS Group Office

We have opened a new administrative office to support our operations.

The address is:
545 Orchard Road
#10-09 Far East Shopping Centre
Singapore 238882

All medical services continue as usual at our four clinics.

Thank you!